Preheat oven to 350°F (175°C). Grease a baking dish.
Season chicken breasts with salt and pepper, then place in the dish.
In a bowl, mix soup, sour cream, mayo, Dijon, garlic powder, onion powder, and half the cheese.
Spread the sauce over the chicken and top with remaining cheese.
Combine crushed crackers with melted butter and sprinkle over the dish.
Bake uncovered for 40-45 minutes until golden brown and chicken reaches 165°F.
Let rest for 5 minutes before serving. Enjoy!